The entire process flow is controlled using Siemens products: The Opcenter Execution Pharma MES is used to orchestrate subsystems and processes and to analyze their quality. Production processes can be automatically developed, optimized and managed. mRNA processes encompass a number of manual work steps, such as weighing, which can now be performed by Siemens weighing systems, as precise measurement of weight is vital for product quality. All systems were modified for automation using the Simatic PCS 7 process control system, which controls and regulates the system processes. Other products used include network technology, WLAN access points, communication technology and the TIA Portal engineering framework. Siemens supports system implementation for production startup at BioNTech with in-depth service and on-call readiness. Siemens and BioNTech enjoy a long tradition of partnership collaboration and have intensified their cooperation for Covid-19 vaccine production.